Which NTR-focused game just has the most fucked up corruption in general? Like it's really messed up mindbreak in general.
I'll list some of my favorite titles here. All have some degree of what you're looking for.
Bitch Bokujo's NTR Knight; (RPG, fast corruption game that turns the women into sex-crazed pigs pretty fast. Some people don't like how "fast" it happens but it has a lot of mind break stuff);
A promise best left unkept (VN, great game in general);
Little Boy's Human Instrumentality Project; (Some endings go into some DARK mind-break scenarios. You've been warned);
Dark Hero Party (as someone said - depression simulator RPG here.)
Circle Gyu's games (Rpgs, girls usually start innocent and end up world-class whores fucked by pretty much every man that exists in that universe lmao. All of his games are good)
Cli Pick's games (Rpgs, even though I'm not the biggest fan of his art, they hit hard - most games have lots of unconsensual stuff until they get to the hard corruption part though. I recommend Nitro Nil and Mind Luda)
Waffle's Hajimete no Kanojo (VN, be careful with this one. Infamous for having no good endings and being "soul crushing");
Scars of Summer 1/After (RPG. Hits hard as fuck - especially 1.)
NTRPG 2 (nuff said. It's ntrpg 2);
Henteria Chronicles 1-2 (Rpgs, 2 is better imo);
All of Shibahu Cement's games (All rpgs. Most girls end up as sex-crazed sluts in all his titles - especially the ntr ones);
Frog Shelter's games (Rpgs. Especially RJ01066599 - goes pretty hard on the mindbreak thing by the end);
Nitowa's Yuri And Claire (RPG. Great game - kind of long though. Corruption was super well done).
And lastly, NTR Party by Takeda Hiromitsu. Still in development (and probably won't release until like 2085) but even the test version is great - CG/animation quality is top notch.