Pretty sure in the second attempted rape scene on the subway Aiden comes to her aid and they end up fucking in the toilets, at least in my game. She doesn't take up self-defence on every route.
Not sure what started the exchange (skipped some messages in the thread), but you are correct that not in every path she took self-defense lessons. Also, even if she took self-defense, that has to be taken with a bit of "warning".
Even in reality, one lesson in self-defense would not automatically make her go "scrambling eggs"
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if attacked, especially considering the psychological situation left by Anthony.
If she did the self-defense, plus reacted in the previous occasion, that may make her more capable of effectively reacting to the situation in a certain way.
There is actually a variable that keeps track of how much she can do that kind of reaction, and if I remember well, at least for some scene before 5.05, some choice would be possible only if that variable is high enough.