BDSM, Female Domination is for Brianna. But I don't think it's really hardcore or disturbing in the game, it's rather playful.
I understand that Drugs and Group Sex are not for everyone and I'm not 100% sure it will be present in the game. If it is, I will make them optional, like I did for Netori.
Armoreau
This is your game - so you can do whatever you want. If you don't want offend some gamers - make it optional, but I would not change too much from your original plan (unless it is something that you really want to do - like "Yes, it is a good idea, maybe I should do it").
I've seen some developers trying to please game fans and eventually they abandoned their games: because too many requests like "Can you put futa", "Can you add lesbian", "Can we have ONLY lesbian path", "I don't like NTR, so remove it", "They all need to go on the boat trip", "I think that you should do this and that now", etc etc.
So if you want to include "Drugs", "Group Sex", "Multiple Pentrations", "Spanking", etc - just do it. Otherwise, if you start listening all the advisers/experts/gurus/etc (especially if these people are not paying for the game) - you will end-up changing your story significantly and then you might regret it later (which means this amazing game would be abandoned - and none of us wants it).
So far,
your game is really good.