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noera:
Another somewhat substancial SS-like option for 2D games would "TaffyTales", which isn't as refined in many areas but still does many things right - that's of course as long as one likes the way darker mood.
Else one should probably mention "Town of Passion", "Bones' Tales: The Manor", "Meltys quest" and "Teaching Feeling". Most of these cover somewhat different genres but they are all quite good.
Last but not least there are quite a few newish games which do look very decent, like "Daily Lives of my Countryside" or "Life in Woodchester". Especially the latter seems quite similar to SS, SexNote, etc.