We will just have to wait and see, I guess, but I will be very surprised if that won't be the case.
To be fair, it seems that Dots already brakes his own tropes with this game a number of times. No faceless middle aged MC that tries to get together with a barely legal girl, no failed relationship with an unbearable ex (he has an unhealthy current one), no singular focus on a titular girl (sure, both DmD and Melody had other women, but their presence were dwarfed compared to the main one), the sister and the hotel being the core of the story but every other LI had a fair amount of screen time and interactions already, the previous relationship between characters are shown not told unlike with the ex-fiance and ex-wife, it seems every possible target gets introduced from the beginning, and there must a few others I don't remember or hadn't noticed yet.
Of course, there is a slight possibility for the sister not being experienced sexually, and until we know for sure it's a 50-50, but as of now, beside from the cousin, it's maybe the latina girl with the overbearing dad is a virgin.