A lot of feedback has already been given, but I'd like to share my thoughts about things that I haven't read by other users on this board already.
!!!MAY CONTAIN SPOILERS!!!
5.
Dosage. As a fan of the slow burn, I think it would be nice if there were more "steps of escalation" for every type of MCS. At the moment, I think it's ~ 2 doses until you have to switch for MCS-+1. I realize, that this is probably wishful thinking, because you'd have to create a lot of new material, but I think it would make it a bit harder to "speed run" this game and give the players more "meat" on the bones to sink their teeth in.
6.
Outfits. PLEASE, PLEASE, PLEASE give us the option to just click on a set of pre-made outfits. Other games have that option as well, so I don't think it's impossible to implement. I don't enjoy clicking a few dozen times just to switch between casual and professional or slutty appearance. But I LOVE that you included reactions to your outfit. I had to laugh, when "mom" and "sis" commented on the casual outfit during breakfast. It's these little things that contribute a lot to making this game so damn great.
In general, I think this game has the potential to expand. We don't necessarily need 13 chapters by the end and the story doesn't need to be fast-paced. I think the best way to improve this game is to look at what is already there and just make more of that (if the engine even allows that): an even wider range of random events with colleagues and family, more scripted events (taking mom, Penny or sis out on the weekend could be fleshed out more and turned into a whole ... thing), more sexual acts (maybe the option to use sex-toys on others as well as yourself), more outfits etc...
Like I stated in my previous post - I think this game might be the best fan-made, text-based HTML game featuring RL-porn I've seen so far. I don't normally write extensive reviews for things porn-related.[/spoiler]