No forced harem.
Originally, the game intended you to be with Kari. That's iobvious even to a blind man even if you didn't know that. However, the Godess that is Lois became more and more popular, so rather than her just being a mistress, you can be exclusive with her. You can avoid any woman DS, not forced into anyone, though there atimes where it does try to...however, you can ignore that and stay with and faithful to one woman.
There are a number of side girls with not a lot of content (yet) if you prefer one of those, and many, many girls with no content who I assume (as they have a full of set of variables and flags in the code) that will get their time in the sunshine. Kari's sisters, kind of (at the moment...I hope it will change in the future) are a package deal. You do not need to be iny relationship at all with Kari to agree to the baby making (I'll not spoil that plot line but it is not required...Togs has stated this)...but if you agree...you get all four of them.
However, for what you want...the answer is yes when you find one you like, but be aware, it has evolved into a collect them all over time with little blowback to that. Again though, you can play and ignore every single LI if you wish (though kiki is forced upon you...but you can shut her down sexually).