Is this the first time you have played since the Sept 7th or Sept 21st patch? If so, it may be outdated mods. Here's a list of broken mods and replacements, but they won't talk about anything we'd have here so look to updated those as well. Worst comes to worst, try taking out all your CC to see if it fixes, and then add back in with the 50/50 method.
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Are you running a pirated version (no judgement)? Perhaps you downloaded some mods meant for after the patch changes and your version is behind.