Having the same problem with Neala as
Brunnen-G buy tickets and the screen goes black. Additionally I cannot buy a single ticket (she says the "Are you trying to scam me" line) I can only by the ticket book. Black screen also occurs when taking Kimberly to work.
Having Mrs. Jenning's key prevents you from entering several buildings (store, etc.), saying "I need to copy the key" even after copying it. (I was able to work around this by just deleting the key from my inventory)
Also, the stairs inside the rightmost house in the suburb (Lisa's House?) send me to Grandma's house.
Furthermore, the cafe doesn't seem to be working properly. I've never seen Kimberly there, the barista is stands in the middle of the room (no one else appears) in the afternoon, I can't talk to Mrs. Jennings when she's there with her husband
This is using the hotfix. Any help would be appreaciated.