So I've been attempting a "day one" low indecency run of the game alongside my normal run, just for shits and giggles. I have a suspicion if I play my cards right I can get through a surprising amount of content without ever sleeping (outside of the mandatory rests in the prologue). Right now the biggest issues are that I'm basically excluded from the entire crafting system b/c gathering spots won't respawn, etc. I'm also bottlenecked on heals. Technically I can grind for full heals by grinding food points without any risk of being damaged, but this is a porn game and the one getting fucked would be ME if I tried to do that. That having been said, I've been able to coast on first-run dungeon loot pretty easily. Trying not to pay for too much though because money is also a grind to get once I run out of dungeon rewards.
Devotion is also a big issue - area of effect spells are gated behind them, so you need devotion, but you'll run out of missionary spots pretty quickly. Fortunately, some quests reward devotion, enough that you can at least purchase AOE fire and the other elemental spells. I have yet to see if there's enough to get to priest level 3.
I might be forced to sleep and reset the day at some point, but I'm curious to see how far I can go without doing so.