I saw that you asked on Patreon for inspiration for a next project. What type of idea are you looking for? For a game or a comic? Because I think my idea can go either way.
Like I mentioned it before, for a game idea it would be „a day on the Normandy“ or „a hard Varren's life“ or „Alpha vas Normandy“.
As the titles suggests, you are the Varren that got adopted after Shepard went to Tuchanka in Mass Effect 2. Now, an interesting idea came to my mind that you could pick if you want Shepard to be male of female (which could have different impacts later in the game)
The goal in the game would be just like in your Gargoyles – fuck every female and make her your mate. Mechanics would be almost the same – either get them by dominance or by turning them on. You get a place under the engine room right next to Jack. Who could be your first „victim“.
Depending on your skill of how you „play“ other crew members, you get to explore Normandy and find other females for your „pack“ or you are confined to be Shepard lap dog, which limits your „operation“ but still you get to have some piece of action. Here also depends if you chose femSep or male one. If you have chosen femShep, you get to seduce/dominate her as well, but if you have chosen male, you either see him as your rival (dominance) or as a partner (you team up and gangbang females together!)
There's a lot more details I have planed, but that really depends if you are willing to expect the idea.
But if you want to make it a comic, you can just make it like the varren is climbing up the decks – from Jack, to Tali and that other mechanic (optional) to Miranda, Samara and Kelly. And of course femShep and Kasumi if you feel like it.
Of course that's just my 2 cents. If you don't like Mass Effect idea, you can always make number 2 comic of BattleCat with Teela, She-ra and Evil-lyn.
Or a comic about Krypto the superdog with Wonder Woman...