Found some bugs :
- I got stuck while fighting trog (cant click on anything)
- Got stuck on police desk while reading report : quit button wont activate.
May not be the same thing, but I have had mouse not be responsive from time to time.
For me it is probably cause by my fat-fingering the shift key.
I have normally fixed it by tapping control once or twice, and sometimes the shift key. (Then the mouse comes back normally)
May not be same, just mentioning something that happens to me.
( I have not had this problem sense I move the game to SSD, but was having it on a usb drive installation, I was thinking because of slow response time)