So it seems you´re having still BR11 and you run the registry fix?
It´s a good idea to switch to BR12 to hold your game with all the mods at state of the art. This brings less errors than only updating your old BR11.
I always download/install completely new and keep my old version as backup til the new one is well tested and running fine - so u must not fear to forget something to transfer to your new game.
Here is some about keeping you personal mods, cards etc
https://f95zone.to/threads/honey-select-2-dx-r11-illusion.53457/post-8636239
Uninstall the old one is simply deleting the game folder, but if you´ve registered in windows maybe you have to skip the registry entry e.g. with CCleaner or similar.
2 additional recommendations:
your file pathes should as short as possible, for you e.g. D:/HS2-R12 (skip "Illusion")
and do NOT run registry fix - the game runs best standalone.