Release desire is pretty useless. While you CAN have some use from this early on IF you will concentrate on Mind early on it's quickly becomes useless.
Resist orgasm is a way to gather some perks that otherwise require massive gangbang to even hope to achive, but it is something that is needed closer to end-game than early on.
Not having "low mind" by itself but the fact that the max level is caped by your progression (and capped overall) and the level ups work from rising stats. Among 3 "bar" skills Energy is more important than Mind. Stamina is more important than Energy, especially for Stamina Regen builds (both Battle and Non-Battle), so generally you don't want for Mind to have large growth bonuses and when you concentrate on mind first then it is unevitable. I mean, you can, you even can be succesfull, but you will be forced to make like 2 times more clicking every battle than with more streamlined builds.