Hi!
As far as i inspected during gameplay with this mods:
NickNo's Mod Installer - working (but outdated?)
Random NPC Breakups - working
Propose Sex To Companion - buggy (changing genders happen)
Pimp Your Girl - working
Beauty Expansion - working
Cover Tracks - working
Better Pregnancy - buggy (no pregnant womans appear, questionable fertility and pregnacy)
The New Goodbye - working
No More YouTube - working
NPC Relationship Manager - working
Dungeon Mod - working (still a bit of beta)
SugarDaddy++ - working
Set Relationship V3 - working
Party And Nightlife - working
Porn Empire - not working
(i'm not listing the presets, or what i no use now)
None of them breaking the game. The game start freezing about minutes, depend on your game settings and a map size and details (if you check the random building generation on a big map, it will be painfully long time to start/load) Start your new game in default setting (or lover it down),then later fine tune for yourself what u need.
Good luck!