I'm using a rooted Samsung Galaxy A51, on Android 11.
I have installed the latest JoiPlay version along with the latest Ren'Py plugin, from Patreon, with a $1 pledge. The latest version is dated 2nd of July: version 1.20.032.
After installing JoiPlay and unzipping the compressed version of the game, add the executable -> long press the game's icon and choose Settings. In there you must activate the following: Use Less Memory, Less Updates, Model-Based Rendering and Recompile Scripts. Also, deactivate HW Video. In any case, depending on the specifications of your phone, the settings I've mentioned are those you should play with. Test until it gets past the calibration screen.