Mouse movement and clicking are responsive as normal, but the graphic of the mouse pointer is not synced and gives the appearance of significant graphics lag. Only major system change besides playing a newer version of the game is updating to version 2004 of Win10. Running on a 4K monitor, issue only happens when fullscreen and goes away if window is not in focus. Maximized window acts normally.
Noticed Nvidia Control Panel is missing while putting this together, may have been lost when updating to Win10 2004 last week. Will address that and see if something changes.
Update:
Updated Nvidia Drivers to 451.67, no change.
Manually started Nvidia control panel and noticed refresh rate for the monitors I wasn't playing on were incorrect. They are 144hz monitors and were set 60, the 4k monitor I'm playing the game on was set to the correct refresh rate of 60hz. Corrected and no change.
Restarted, confirmed control panel and nvidia service was starting automatically now. Reopened all the same programs and windows I had up before restarting.
Mouse working normal now. Would assume driver update was the fix but hard to pin down since there's no error log to investigate.
Update 2:
Issue slowly returned, was not instant but become noticeable over a few minutes then back to as laggy as it was before. Mostly just annoying as the actual mouse is still responsive, just the graphic is lagging behind what I'm inputting.
Update 3:
Actually found a fix
Was attempting to see if borderless windowed would affect the game and hit F3, brings up a performance menu I was unaware of in Renpy. Performance was set to powersave. Clicked powersave and it switched to performance, mouse movement perfectly smooth now.
Line 148 of preferences.py is what set it, Preference("gl_powersave", True). For some reason, this being set to true limits my game to half refresh rate when fullscreen.