Sorry, I have to disagree.
I always opt for compressed once it goes much over 1Gb.
Usually my biggest problem with them is that I have to wait while those brilliant compressers get to it. But I'm happy to wait.
When there have been issues, it's mostly with the code and I don't see how compressing would affect this, but I've shown my ignorance enough today. That said the minor issues which make up the vast majority of the issues I have had, have taught me a little about snooping around both the console and the games files. So it's not all bad.
YMMV, but don't forget also many people are on limited speeds and data allowances, so I think there is a very valid place for compressed versions.