Just leaving some information in here that my benefit those here. With Wine, I've got XP, VX, and VX Ace set and running fine. With RPG Maker MV, it's really hit or miss. I've tried rpg maker 1.62 from here, nwjs versions 0.44, 48.1, and 3 other nwjs versions on Linux Mint 20 (Ubuntu 20.04). On 0.44 and 1.62, the games performed perfectly with one issue- Can't save. No matter what I do, it's not able to save. AT ALL. That's really annoying.
While playing the Linux version of Peasants Quest 2.11, i noticed the structure is different than the usual setup I see with RPG Maker MV so I simply switched out the www and locale folders with those from a windows game and it ran the games and saved. Since then, I've tested with several games (15 so far) and they all work with one interesting twist. Some games like "Aliens in the Backyard" and "Konosuba Beauty Contest" have a weird text issue where it displays "{intro1}" but doesn't show the actual dialogue. But at this point, it's a much better option than anything else right now because it actually runs and saves at least 90% of the games I've tested this on. And to me, it seems to be easier to me to fix the font issues.
Any ideas?