Yup, forgot of spoilers, thanks.
I've been on both sides of the siblings vs. roommates fight. No more! It's Ocean's problem how to define N&N relationships, I just enjoy the show
If you ask me, the only difference in blood vs non-blood incest lies in pregnancy taboo. That is, the increase likelihood of genetic anomalies in blood related pregnancies. So, there is additional taboo in creampieing a blood related because of that. A way to confirm this is that perfect birth control essentially kills this taboo in my opinion. Or even better, think of a blood related but infertile incest.
All other relationship taboo remains. That is, the negative perception of society, the uncomfortable change in perception of the two committing incest, the conflicting desire between what is right and what is feeling.
In the end, incest taboo is hot for being forbidden. Kill this and you kill the taboo. So blood related is just more forbidden for child risk.
Further decomposing, succesful incest tabboo requires both
1) probabilty of getting caught sufficiently high
2) cost of getting caught sufficiently high.
That is why "harem incest family" is for me ridiculous and pointless. You kill the hot element of incest by making everyone accept your relationship. If not everyone, the people you most likely care the most.