Jenna, the main character, is lesbian (or bi with a girlfriend) at the start of the game. But the corruption mechanic makes women, men too I think just harder to tell since the only playable male is gay, give into their perversions. So Jenna eventually comes to enjoy male attention, because her mind is being corrupted to enjoy semen and really any sort of sexual encounter. So there will be some F/F scenes, some M/F, M/M/F, M/F/F and orgies. There is one futa character, and there is an option for Jenna to buy and wear a prosthetic penis of varying sizes. There is also one ending that has been implemented that Jenna has a choice to have a penis for the final scene, but again it is optional. Also, you almost always get to choose your whether your partner is male or female and can deny Futa or lesbian content if it isn't your cup of tea.
There really isn't that much F/F content to be honest. Usually a man is still involved in some fashion, and most scenes that are exclusively F/F are really more of Jewel or the director, of the pornstar route, teasing Jenna.