I honestly don't trust any of them, well except for the sisters. They seem to be less inclined to rake you over the coals. Especially considering one hated you for coming back and the other was a recluse of the highest order.
I just can't handle getting doled out tidbits every episode and being strung along by the nose. I think I have to wait until it is nearer completion to progress further. It is multiple times worse than getting cliffhangers on your favorite weekly shows. Awesome game, great content, but man the unease at pondering when the other shoe is going to drop. Not going to lie, my favorite play through is the manwhore, so I know i am doomed.