Im running two playthroughs - one where its yes to everyone just to see where the content takes me (as im pretty sure closing paths could close others... if i reject say Bailey do you still get foursome scene with her, Zoe and Liz if i am pursuing those 2 by contrast?). As for my other playthrough which i consider my canon one im not as im not remotely interested in Penny as well as several other girls including the Porn Star, The lesbian lovers, Tia, Jasmine, the old nurse and Stacey.
On the fence with Yen and Bailey (they offer fun times alongside girls i really like) and going forward will rejecting the likes of Skye, McKenzie, Emiko, Rainne, Harper etc in the future too so ive one much shorter playthrough where its just the girls im invested in (stuck with sodding Jaime and Shauna hogging screen time though...). Cant wait to see more content as we progress with a few such as the Teacher and her Milf sister, Moon and her sister, Mabel the teasing nurse, the chubby jogger, Willabelle and Willow (shes hot, fight me! lol)