You'll get to interact with a futa character as a man regardless, just 1 of them (Nari, the thicc lady at the space port, where you go expeditions).Which character has the best content? Male or Female? In the previous game preferred to play as a female character (because of the small difference and to avoid GAY ( FUTA ) content on a MAN) ...
Your gladiator on the other hand will get to have scenes with more futa characters (2 or something, the jade queen scene probably has some unknown condition that no one know how to trigger, or it isn't implemented yet) if you intentionally let her lose.
If you can even make it to those fights to begin with, good luck swimming through the ocean of bugs that is this game.