That pandora's box is the biggest bullshit I've encountered in an rpgmaker game so far lol. Trying to not to cheat it but it's not worth it. Grinding levels, getting the best weapons, even spamming sleep potions and bombs as I read. Ran out of everything and still it won't go down, it keeps switching and healing over and over again. Everything else looked like playing in hard mode to compensate that you can craft items and that you are just an alchemist and not a warrior, doable, but that boss just went overboard.
Overall the game looks like a grind. The TP system is annoying as fuck at least until you farm enough items to carry food. Then it's a chore. Everything consumes it, be it fighting, fleeing, gathering, crafting, even moving maps or warping and some skills in combat. And if you go to bed at 30 or below you get a permanent 20% debuff for stats and tp until you spend 500 hells on a potion.
I like games with crafting systems so I gave it a try, but the artificial challenges ruin it making them be just a burden of a daily ritual.