Only bad options.
Elena learns about Jen's affair with F --> E dump's him. Maybe even when D is around --> Game over.
D finds out about F + any other girl --> Game over
Only plausbile development I see is D getting involved with E, having fun with her. Same time relationships between D+F and E+F progress further. After some time they confess each other they have sex with the 3rd person of this trio ... ménage à trois is settled

Next step ... everybody has to fuck Olivia, Jennifer, Koko, Cassandra, Gorgina, ... ménage à huit?