I don't think it would be a bad move to have players reload a save, if they fuck up somewhere. It would only add to the danger purported by the setting.
I'd rather not if you are talking about constant game overs. Unless it is video game with mechanics and gameplay that support something like that (ex.
Metal Gear Solid games or horror genre), then it just becomes annoying very quickly. I don't think visual novels lend themselves well to game overs. Reloading a save, yes I do that often (usually to grab a new lewd scene), but a game over screen mid-story? I haven't found one yet on F95 with constant game overs that doesn't royally piss me off. Fortunately here I think the zone is the only time we have approached something like a hard cut game over. To its credit the "bad end" there was easy to spot coming and avoid.
Rather than game overs, there could different outcomes (good outcome, ok outcome, undesirable but not deadly outcome). I quite liked the dilemma we were faced with during hive mission. But the problem with the previously mentioned different outcomes is it requires
a lot more writing and rendering. The more outcomes, the more branching required. Great for players but a chore for developers and I would be sad to see DS become another once-per-year update game. 3 to 4 months is ideal, especially for kind of quality entertainment we receive in DS.
_somewhat unrelated section _
Recently a number people have called for changes to certain aspects of story or characters (I also asked from time to time, oops), or they have wondered why this game can't have a weaker "more realistic" MC, but it never seems to turn out well when a developer caves to the wants of the general public and changes their original vision. imo, this game has a high level of support and praise precisely because it has gone its own way and takes a different tack than most other games on F95.