Uhhh, i wonder who's the most fucked up of them all? normally i would say Stacy, but Naomi and Belle are freaking me out badly recently :/
Oh well, whatever: Jane is love, Jane is life (oh and fuck u, Kiara!)
I have a strange feeling that Emily is the most fucked up.. something disturbing about the girl's behaviour, popping out of nowhere most of the time, also the fact that there are no action scenes with her so far. Could all be a setup for a finale twist.
Aaanyways, all of the patients are fucked up in their own way:
Stacey might have DID - personality disorder, which explains shifts in behaviour/mood/memory. Or she is indeed a religious fanatic which is disturbing in its own way.
Belle is a case of creepy nympho, so far it seems to imply that this was a result of childhood psychological trauma (there were hints towards father abuse, potentially the worst kind).
Violet's problem is also deeply psychological, and I have a feeling it's a twist on Misophonia - where claps trigger orgasm and some other specific sound triggers loss of self-control in terms of violence (beating up her trainer is not the only case and perhaps connected to the issue).
I cannot quite figure out Naomi - seems like she's not a simple case of self-absorbed narcissist (which is pretty standard for kids of super rich parents), but I avoided her content in both my playthroughs simply because I can't stand that personality type. It would have been so much more fun if she was the shy type in the game, thinking she has a curse on her pussy or smth like that..
All this is speculation of course, and would depend on where the writers would take the story - if they choose more dark and disturbing path (shoutout to Lessons in Love) then all above would be quite plausible.