1. Don't level up the tablet too high (more specifically, the Stark info on prison) or you lock yourself out of getting Nat her 5th strike and following anal scenes.
1b. Note, you can use console to set "nat_waiting_to_steal_another_enhancement = True" to cheat your way past this, if you don't want to rewind saves/start over.
2. Note that progressing the main story to the escape phase will lock yourself out of the Nat content as well.
2b. My suggestion to the dev would be to make the escape dependant upon having done that content, or be clear that once you go through with the escape you are locking yourself out of some content.
3. Once you get past the escape phase, there are a couple of things that are dependent upon each other.
3a. Stark needs Rocket's help.
3b. Rocket won't help you unless you get She-Hulk to show him her boobs. Consistently.
3c. She-Hulk obviously needs to be... altered, in order to be comfortable with this. Helping her with her lesbian problem is a way to get on her good side. Stark is helpful in this questline.
3d. Meanwhile, Falcon is pissed off that Thor+Nat is gone and will require you to do something for him with Emma.
3e. Also, Emma wants something from Rocket as well. Again, Rocket won't help unless you help him with his problem first.
4. Note that successfully progressing the Nat storyline to the end will end the game currently. You can always answer the final question "wrong" and it'll keep going.
Now, for my questions;
A. Is it possible to get the She-Hulk+Tatsu scene somehow? I've finished training, and the MC says he'll ask Tatsu for a good time, but I can't seem to progress it further. Have boosted Tatsu's boobs a few times already, can't seem to get anywhere. Never mind, I just had to do the full masturbation scene one more time in order to unlock the option with Tatsu.
B. I assume the Harley scenes in the lab are work-in-progress and it's not going anywhere yet?