It's a stab in the dark, but any chance you are clicking on the wrong HI.exe file? One is 64 bit and one is 32 bit. If you're sure you are using the correct one, try this ... First you need a backup of the game and any save files you have. 'Save' are in their own folder found under the game folder. Copy the saves folder somewhere you can find it again. Desktop, thumb drive, another hard drive, etc. Now go to your 'C' drive and find the 'Users' folder and within that the one with your name. Within that folder will be a folder named 'AppData' (You must have show hidden folders enabled) and within 'AppData' is a folder 'Renpy'. Almost there. Within 'Renpy' will be a folder Island-xxxxxxxxxx. Delete that folder and try restarting the game. The folder you just deleted is the first folder the game examines to see if there are any saves, etc. When it doesn't find said folder it will create a new one. The reason you created a backup copy of your 'Saves' folder is should you have to do another clean install you won't have lost them. Good luck.