I have to agree that not doing some fetishes (Incest, pregnancy, hardcore, etc...) may be detrimental.
The main reason for these fetishes is to add some "spice" to the story, make it more out of the ordinary by touching otherwise morally wrong aspects of sex. It add something else to the scenes. Like "Fucking the superb MILF next door" is something, but if that MILF is your aunt, it make it quite more interesting, since the "wrongness" of the story and such make it more exciting. It add drama and moral questions and choices. After all, games are made to do things we couldn't possibly do IRL.
So if you go with a mostly vanilla story, it will need to be next level in term of writing, visuals, scenes or characters. And what i'm saying by next level is really trully amazing details worthy of awards and stuff. Which isn't a realistic expectation, sadly, due to your lack of previous experience.
If i may add a bit of personal story, i used to do 3D character animations. So using those skills, i'm confident i could make much better animations and poses than most, since most don't have the professional training i had. But my lack of programming skills and slightly lazy attitude would impede in a good making of a lewd game. Also, if try this out one day, i do NOT want to make a average bland family story. Maybe i'l try it out eventually, but not now.