I'd like to add on to 3. Estrus enemies are actually pretty easy to deal with in 1 v 1. All they do is grab and are vulnerable to counter attack. All that's needed is to either block or dodge the grapple and you can then hit stun them with attacks afterwards. And on that hit stun, it works as long as the enemy isn't attempting a grapple. I.E, you can trade hits with enemies because their basic attacks don't have 'super armor.' If you attack while the enemies are grabbing at Phil he will get grabbed either before or after the hit lands. Unless of course the hit lands and defeats her.
If several enemies are around attempt to run if possible. Watch out for estrus wolf girls if you are running, they're far faster than Phil, and make sure to dodge their grapple attempts. If you Phil grabbed against a wall, good luck because your recovery will probably give her another attempt with your stamina depleted.
In summery, on grapples. Avoid if possible, avoid getting grabbed against walls at any cost, and similarly avoid getting caught by groups by means necessary.