I agree that Lexi is awesome. As for Chapter 5, you can run a Lexi route without a Holly "bonus/addon", that's how I ran my Lexi route. I actually replayed it later for the Holly content and prefer it without the threesome, so I dont even look at Holly's breasts on the balcony... and yeah, she and Holly kiss on the yacht, but you and Holly kiss outside the hospital, so...
Anyway, As I have said before, Cece is my fav, but only barely. Lexi is my second favorite and was my initial focus on my first play through, however I didn't finish that play through but went back when Linda professed her love at Lexi's and played through with Linda as the main girl, until Cece left her note, then I went back and played through with Cece as main LI and finished, then I finished Lexi's route and then Linda's.
At the moment, I am in the process of learning Daz and Ren'Py and plan to make my own VN's in the near future (I have 10 planed so far) and I hold LOF as the model to measure my own work against, which is honestly quite a high bar!
In at least three of my VN's, I hope to have some type of LOF cameo and I intend to use the Lexi Route as canon for my games. Even in the one that takes place on a small moon colony(not Earth's moon) in space in 2336.
I plan to have the MC name his ship (his final biggest ship) the Dimante after his mother's favorite Old Earth musician.
(He goes through 5 ships from a tiny 1 person craft to a large vessel with a crew compliment of 6 to 8, and I plan for his second to last ship to be named "The Sunset" as a nod to a certain yacht in another game)
In another, I intend to have the MC share a bus ride with a young black haired girl who strikes up a conversation with him because she looks in his eyes and see's that he needs... something. She sees that he is reading a newspaper article about Lexi getting married and, to break the ice, asks if he likes Lexi, and he says "Of course, who doesn't" and she says I know her, and her fiancée. So they talk and she gives him some advice that helps hm as he goes through the rest of his story. When they reach his destination, they say good bye, he gets off, and she continues on.
So yeah, just because Cece's my favorite, doesn't mean that I don't absolutely LOVE Lexi as well!