Honestly kinda curious how professor plans to end this, i don't think Lacey bullshit will end any time soon since brain damage is permament and the bitch has to take notes which don't matter anyway, because i doubt that when situation arises she will stop in her track to open her notes app and read through 1000 notes, unless there is miraculous fix for her she is destined for failure
At this point its either technical magic or real magic would be my guess, technical magic, by that I mean like so many things currently with the game its going to be Deus Ex Machina into a solution, I mean look at the drugs, they don't do what they are supposed to be doing by a fairly large stretch, people change on an Act basis without any natural cause. So either it will be that, or considering this game exist in the same reality as Augusta, which has clear supernatural forces in existence, either way its what I expect, not anything remotely realistic in term of plot development. However that being said, I have written what I assume Act 4 is liable to be, like a page or two back, and some vague notion if that is the case what Act 5 would somewhat look like, if my theory does happen it would still be Deus Ex Machina, but I guess vaguely satisfying.
Like I mention I assume Act 4 the MC will have went thru a personality shift, where some other persona will have taken over and I assume proceed to do everything the MC held himself back from doing, namely fuck every attractive women around, Lacey & his girls are going to go after him, find him and Lacey will effectively be faced on what the other side of the coin looks like, namely having to see her husband be a manwhore. I assume after she had a bit of a mental breakdown over it she'll figure what worked for her sorta in College would work for him, she'll convince him to fuck the Hell out of her, causing him to undergo a 'reset', but rather than be back to quite what he was originally he'll be sorta an amalgam of the two, so he'll have his will and confidence returned to him, and he'll be alot more willing to fuck around.
Act 5, they'll go back home, discover the MC & her lost their jobs, along with a few others, under those conditions they'll have to move to Lacey's ancestral lands, where Lacey will have to process the various issues her husband had to face, namely that he changed, that he fucked a ton of girls, and that Act will largely about that process all the while introducing the big bad guys, by the end of it she'll have suffered her own small mental breakdown which will lead to her two persona to also fuse back together, stabilizing her mind also. At which point the brain damage will all be wavered away in the name of 'healing'.