"Virgin" run on very hard (admittedly dropped to easy for the succubus) - Lv 100 with almost all diaries (I think I'm missing 2), all but 1 weapon, almost all encyclopedia (missing 6 enemies + the 1 weapon). 150 karma.
Completed the game with both endings (or I guess the "official" ending and the unofficial dark ending).
I managed to get a Virgin run on very hard last year prior to the updates (you can see my previous post in this thread).
For the Succubus, you need to bring a Defender greatsword (no need to level or spec into its stats) to block low level attack spams.
When the Succubus does very hard to dodge attacks, just pause, switch from your primary preferred weapon to your trusty Defender sidearm, and then just hold it up.
After that, it's just learning Succubus patterns. I can post my recording from a year ago later.
I'm sure you know this by now but: the meta weapons were low commitment ones. High responsiveness and good thrust. I used Bone-carved Kris (ascension path?) for the hardest bosses I want no risks for. Crusader's Straight Sword (Light) was basically the same but a little more risky because thrust was on the 2nd swing, but it has 4 consecutive combos so overall dps done is higher, more damage done before retreating. Unmarked Katana (Normal) was almost as amazing as the above two but manages to outshine neither, so it's actually not as cutting edge as I expected. Forgive me, Katana fans out there.
Don't know if new update affected this and how much I have forgotten lol. I'm trying to hunt through the thread for a good translation before starting. My old file seems to cause text unhooking.