Sadly no, because, based on what I gathered from all the tests that Matto did, Vulkan support for Unreal 4 is abysmal compared to 5 and many plug-ins don't work natively, so we got crashes at pretty much every point while the loading of the game...DXVK is different because the switch to Vulkan happens at a different point in the whole loadin/rendering process...As a thought - maybe Vulkan would work better in this case? We already know that DXVK helps with eliminating crashes. It may make things worse for NVIDIA but in this case it should be possible to create a DX12+Vulkan build which dynamically chooses a render based on videocard vendor.
Also, the issue is limited to a specific single component in Unreal and not with the GPU, but with DirectX: RVT in U4 is incompatible with DX12 and RDNA2/3 apparently forces DX12, so the game crashes because the plug-in is loaded in DX12, not because of AMD itself...if you were to add -dx12 and load the game with those argument with Nvidia, RVT would still crash the game...the issue is equal part Unreal, because they never fixed this known compatibility problem, and AMD, because its compatibility sucks with older Api and they force the rendering on the new ones (apparently, because we are not 100% sure that this it's what's really happening on RDNA2/3)...