Game work this way, you can not do so things until you do some story thing. Same goes with pregnancy there is order in girls to get pregnant etc. it means you missed something. Sometimes you just need just to sleep alone in room to proceed futher in story etc. Or maube you lucky guy and found some softlock.guys for some reason i can't continue angela route after giving her sperm, the in-game dialogues keep saying that i need to ask tiffany about the radiation, but i have already make it to the settlement and have y-shields, how to fix this?
Also what mods you installed? Multi mod for examole include inc. patch so no need to install it.
P.S. Just to be sure i played game many times before, and almost have no problems, problems always was i missed something to do myself.