I usually prefer to focus on specific routes in games like these. For GB1 I wanted a Nax only (except for lesbians) playthrough, for the sequel I will probably play each route separately and avoid mixing things up. So if you offer a Nax route I'll try getting the characters with Nax and no other man, if you offer a troll route I'll try making all the girls get it on with the troll and no one else, and so on in different playthroughs.
In Project Myriam, for example, I like the husband route (he's possessive, abusive and all) and I played it avoiding every character but him. I was extremely disappointed when near the end of the game he insists on having all his coworkers fuck his wife for some unknown and unconvincing reason, even if that's just him being controlling and mistreating the MC, because that playthrough was about that spcific character.
But, yeah, seems like the butcher will come out victorious on this one, sadly.