It's actually pretty relevant to the story in this game, in my opinion. The story makes a lot more sense if you play it with the incest patch, since the story was originally created by Alishia and Elizabeth to include incest, then had to be changed because of Patreon censorship.
Here are two examples of how it makes more sense with the incest patch enabled.
- MC and Sasha are identical twins in the incest version (except for their genitals, of course), which explains why their faces look exactly alike. In the unpatched game, they're just roommates, who happen to look exactly alike through unlikely coincidence.
- With the incest patch enabled, the MC and her sister and mother go to live with their grandmother. This is feasible. In the unpatched game, the MC and her roommate and landlady all move in with a fourth unrelated woman. If the MC is moving out of her landlady's place, why would her landlady also move out? Let's say that the landlady lost her house due to a foreclosed mortgage. Okay, now everyone has to move. Why are all three of them (MC, roommate, and landlady) moving to the same house, which is not an apartment complex, and which is located in another city? Do they all like each other that much? Nope. The MC and her roommate don't really get along, and the roommate and the landlady don't really get along. And why is this random woman in another city opening her home to these three strangers?
Perhaps this is all explained perfectly well in the unpatched game. I wouldn't know, because I've only played it with the incest patch enabled. But even if there is a reasonable explanation given, it seems to me that the circumstances are much more believable when the game is played as it was originally envisioned by the creators.