Im coming from 0.42, the last one to be updated here. I only found the content between Frank and the college girl, two or three pictures nothing more, the one with the hospital (the interaction where you can touch the boobs of the black woman) and Natasha worked (But it bugged for me there soo i never could see her in bikini). Thats practically it.
Mayor/Natasha story could be solved in 2 ways as intended in v0042
On Frank/Kelly a few scenes have changed but still the quest end WIP.
At hospital is few more content and mainly described how to get inside.
Dr.Jennifer got a story.
Melvin finally could get his picture of his girl.
bugs are almost eliminated (a few ones you could read here but seemingly out of old save-files or editing) and the debugger (if you trigger "bugfix" on laptop seems to work as of feedback)
The relation balance for Cecilia and Audrey were reworked.
RV party reworked (best outcome for previous variables still a misery ^^)
Lockpicking something added and could be used (2 doors as far i figured)
Ingame hints could be triggered to showt for started quest in a proper underlaying layout for each
.....
From v0042, in my opinion, it's a really huge change to reaveal older content more easily but also have a few new content.