Greetings my friend... What a clever way to disguise your question regarding the rather obvious elephant in this room.
Hahaha
The futa/trans tag is misleading on this title but still appropriately placed above the title. There is one character that is fully transitioned from male to female, she is not ashamed of this and freely tells everyone she meets of her prior gender identity. Otherwise, you would never know she is trans. This is why you see the futa/trans tag on this title.
Having said that, this story has three protagonists available to the player at the start; hetero male, hetero female and lesbian female. You have the opportunity to play this title as any of the three and to repeat the game to see the story through the eyes of each character should you choose to do so. There are a total of 9 potential LI, 3 of which become available to the player depending on the starting character selected as the LI are drawn to the MC based on the tight living quarters, loneliness and of course, their sexual preferences. There is one bisexual LI that is available to both the lesbian and hetero male MC but there is no other crossover. So, to meet everyone intimately it requires a minimum of 9 total plays or you can play your favorite and call it a game. There is no right or wrong way to play.
However, this fascinating story takes place on an undersea space station with various scientific studies going on. MC is the new security officer, brought in to replace one who is tragically no longer among the living. That is the mystery you must solve here. That is the source of the intrigue for this story, an extraterrestrial murder mystery... or was it even murder at all? Hmmm... So many questions to answer... Personally, I plan to make 10 total plays through this engrossing game. One for each of the LI available to each of the three MC types and the 10th with no LI at all as there is additional content available to you if you choose not to be intimate with any of the LI. Being a hetero male, my 10th play will be with the hetero male. As I understand it there is no difference in the content for the no LI play based on who the MC is for that play through. Otherwise, each play will have similarities and differences. Honestly, I want to see if I can solve this mystery prior to a big reveal at the end. The game is just starting and I am already enthralled. This title may or may not be for you, Dysphorika my friend. Yet, I encourage you to give it a go as it has been lovingly and painstaking created by the two amazing devs who gave us the Elsaverse. The brilliant story sense of Tlaero and the vivid, life like art of Mortze come together to make this a stellar game that is well worth playing. I hope that helps answer your curiosity.
Adventure ever on, Phat