I dunno what you guys are smoking, this is a game where you have to sit there with the guide open 24x7, there are LOADS of decisions you can make that will lock you out of other things. The order you do things in is very important.
For example, if you progress Mira before Emily you are semi-fucked for a while, because if you want to upgrade her house for the orphanage (which matters a LOT if you start knocking bitches up) and upgrade your own house, you will not be able to, since mid way through Mira's path there comes a point where once you enter the church, it kicks off this whole bullshit quest that you are supposed to be around lvl 25 and well prepared for. So... since you need to go into the church to talk to the priest about the orphanage before you can upgrade the house, now you are fucked until you level up and progress a lot.
If you progress Penny's path before befriending Tia's mother, you cannot choose to have her help (which is the far better option) when Penny's useless idiot husband shows up and needs medical care.
In the half-orc village, several decisions have unclear consequences that are not logical. For example, if you want to kill the chieftan's son (the idiot who murdered his father the chief) when you come back with evidence that he did this, the best option is actually to *NOT* present said evidence, and just straight up challenge him. What... sense does that make lol... Also if you tell that guy asking you for advice to give the dancing girl wine, it effectively locks her out of anything... all she does after it sit around the fire and finger herself, no option to bang her, and nobody else seems to bang her either. That outcome was not at all clear.
There are situations like this throughout many/most of the paths. I just listed a FEW small examples. You will almost certainly need to do multiple full playthroughs from the start, to see everything you want to see. And the game is not even close to done yet.