Well, I'm not a proven expert on this, but even I can't understand these statements.
According to my definition, Ashe has four very distinctive FEMALE characteristics:
1. she has very feminine facial features
2. she has a distinctive feminine stature
3. she has very distinctive feminine breasts
4. she has a female reproductive organ. Here we don't (yet) know whether she is "fully" equipped!
For me, she defines herself as a woman, also under the aspect that she has a male reproductive organ as a "bonus" (where we also don't (yet) know whether her sperm is "fully" equipped).
To nip any further discussion in the bud, I would like to refer to
THE PERSON who should know: the developer -
IT IS AND WILL REMAINS HIS GAME! and his statement leaves no room for misinterpretation!
Anyone can read it in POST #1 in the "Developer Notes" section