If you tinker with the script.rpy file you can do things like tweak the stat caps and starting minimums. But I think the changes only get applied if you then start a new game after making your edits.
I managed to tweak the game to make it so the MC started with 200 energy and that 400 was the max that could be gained with sexual skill points. I also raised all the other stat caps to 10 instead of 8. (Heh I even managed to tweak the age ranges for NPC spawns so I'm no longer getting any employees older than 36.)
I tried tweaking the MC's minimum arousal to be higher but I haven't had as much luck getting that to work. It seems like even if the MC defaults back to having enough arousal to be hard there's some check that's being made elsewhere that's still blocking him from pursuing further penetrative sex if you orgasmed your last turn. Although you do then immediately get hard again if you take another turn doing something like kissing and groping if you have enough minimum arousal.
The mandatory refractory period is really annoying though so it would be nice to find a way to get rid of it entirely though... It would also be really cool if there was a way to push these script.rpy edits to affect an already started save file. I've gotten far enough into my current play through that I really don't want to start over just to make further changes. But yeah it would be cool if there was a way to alter those stats / parameters for an ongoing save on the fly.
I guess my description was too short.
What I want to do is to mess with the script or whatever corresponding file I need, in order to make random characters to start with higher energy like 350 and apply it to all characters, instead of going individualy to each new character and change it with a command or the mod.
As per your issue.
Personaly I prefer having a few feisty ladies with higher stamina and sometimes lower max arousal to make them more often.
you can also change your max arousal to be lower or higher so you cum more often or less often.
P.s. in the original lab rats what I did was just change the script from a - to a + so everytime i gave a serum i gained a serum so maybe something like that and where I find it