Two worlds colliding sounds interesting; in fact Nothing is Beautiful imo has been mostly for building a loose background around Arakawas and trivial easter egg purposes (whales, speaking to plants, etc), up until now that the God of Wires controls Tsuneyo and has her spit out the following:
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This being alluding to Yuu or Saki's place is just too possible. If only one day we get to visit that same neighborhood.
In Theory, we may have already visited that same neighborhood.
The Old District may actually be where Yuu and Saki lived, in 'Nothing Is Beautiful', and with the recent mention of Grandma's house by Ami, which seems close to a lake:
It might be a place we'll be visiting rather soon.
Presumably, when Sensei and Niki went to Niki's childhood home, and fucked for the first time, they were close to Sensei's mother's (Saki's) house (Ami's Grandma's house), and by a lake.
There is also that abandoned school that comes up every once in awhile which may have been the school that Yuu, Saki, Miu, and Reina, were going to.