If they're in a relationship with a fictional character that's beyond parasocial since the social is the dialectic between self and other. The Waifu is not an Other because She does not signify anything outside Herself. She is God.
By shifting to a virtual world, we go beyond alienation, into a state of radical deprivation of the Other, or indeed of any otherness, alterity, or negativity. We move into a world where everything that exists only as idea, dream, fantasy, utopia will be eradicated, because it will immediately be realized, operationalized. Nothing will survive as an idea or a concept. You will not even have time enough to imagine. Events, real events, will not even have time to take place. Everything will be preceded by its virtual realization. We are dealing with an attempt to construct an entirely positive world, a perfect world, expurgated of every illusion, of every sort of evil and negativity, exempt from death itself. - Baudrillard