You can keep away practically everything from Clara if you choose wisely. (See my loyal paths walkthrough, which I will update these days if I have the time for it) Some events are hardcoded, but even there you can do something. Clara is the only one you can keep save AFAIK, e.g. Amy has some events which will happen no matter what you do.Edit - just to clarify, by safe I just mean she won't be railed by everyone. Stuff will still happen to her even if you pick you don't like ntr but you just won't see most of it.
Having made a first quick playthrough of v19, there are 2 things finally becoming cleared up by slowburn. As I and some other players stated, the MC is NOT Dave from "12 Days". He is a cousin of Chaz and pops up for the first time now.
Another thing is, you finally get a "confirmation event" for exhibitionism in v19. It is possible to keep Clara loyal and stil following the daring dess/exhibitionism path.