i do want to play this game, but I'm scared of spiders so I just want to know if there is a toggle to get maybe rid of all mentions of spiders, like a arachnophobia toggle ?
Only the boss is truly spider-like. The other enemies are more like spider-centaur-humanoids -- driders is a name for this kind of creature that pops up occasionally. No, there's no arachnophobia toggle. However, as though the developer seems to have had some kind of foresight, the area can be shortcutted in a sense -- rush through from left to right, sticking to the top set of paths, unlock the ladders near the save point in this area, and you're good to go up a ladder to the Path of Eternal Rest. Go left from there, let down a ladder into the slums, and you'd never have to go into the drider-downtown area ever again.
Although if you want to loot-rush the area efficiently, there's a witch with a spell to give you for rescuing her somewhere in the middle (pyromancy/darkness spell somewhat influended by luck), and a strength-based polearm weapon that's a bit slow but can be fast if you opt for the ascension path with the twinkling slab at the end.
The spider boss opens another way into the Sunken Valley, shortcutting the laboratory almost completely to the boss there. If you rush past the spiders and skip their boss, you'll deal with the zombie area, a corrupted paladin boss, and go through the laboratory from the very start to the end.
I'd say the spider area doesn't have good loot for most players, but it's not entirely skippable. The cemetery has a great sacred art (holy damage) sword, a great sacred art gun that hits multiple enemies in a row, a staff weapon that when upgraded on the ascended path makes the best close-range spell in the game get buffed by 2 multipliers to be the fastest way to kill anything if you're a mage... but the cemetery and its boss are 100% skippable.
The best loot of the laboratory is near the end so you don't get much extra coming in from the cemetary. The real prizes are in the Sunken Valley, which overlaps with both routes. Fantastic rings that make magic spells cheaper to cast and weapons faster to swing respectively, a close-range darkness spell, and a rather crappy trick weapon. You also get access to a sub-area with enough karma collected, giving you one of the best swords in the game and a couple awesome rings for magic and crit+luck. Also a magic bottle boost.