Actions and consequences.
Relationships are meaningless if sleeping with everybody isn't a problem, makes relationship building seem inconsequential.
That's also why I prefer games like Rockstar and Twists of my life and Japanese date sim style VN's, there are consequences to your actions.
If you sleep with multiple people you end up with nothing so you have to pick and choose what and who you do.
Take Twists of my Life. If you start a relationship with Ann then have sex with her ... frenemy? ... the friend she hates anyway ... then Ann breaks up with you and moves out. If you date the teacher then try it on with her friend at the club she breaks up with you.
If I start something with someone here I can still have everyone else and nobody says a single thing. It just makes those relationships so absolutely meaningless.
Take Stephania, she's tired of being treated like a slut and wants to be treated with respect, she claims to have feelings for the MC and he says all the right words back to her yet a bit later he's balls deep in someone else and no one bats an eyelash.
Sure I can follow one girls path and ignore all the others but that path has no substance.
It's more like a collection of fuck buddies than lovers.