You guys... seriously. This isn't some TV show where we have no access to the writers and no other way of knowing what's coming other than to interpret the episodes seen so far. We know the structure of the game, we get labeled previews from the dev, and there are regular updates and discussions with the dev with his patrons, on discord, and right here in this thread.
EDIT: Also, to be clear, I think most people calling Drew a villain mean that in a literary/videogame sense. Drew is the antagonist working against the player. It's not a moral judgement, it's about game structure. In this case, villain and rival mean the same thing. There's not much point in arguing semantics about it. Now, if someone says, "I think Drew is evil," that might be different, but let's be honest, chances are they wouldn't be talking about the NTR aspect.
Each update has two NTR scenes. In this update, one went to Hunter and one went to Drew. The objective is to protect the girls from being seduced/raped/tricked/fucked by other people. Drew fucks one of the other girls in one of the avoidable NTR scenes. That is how we know Drew is a "villain." We could speculate that by the end of the story Drew may change sides, fall for Sterling herself, or any other scenario, but as of right now, Drew is working to take girls away from Sterling and is reveling in doing so. I can't even tell if y'all are seriously debating this or just joking around, because is Drew is obviously the "new season villain" right now. It's not even a question.
As for trans content driving away fans... this is basically the same argument as the NTR stuff. My understanding is that WWG has no plans to force trans content on anyone in the canon/main plot, but clearly there will be a fair amount in the avoidable bad ends. This is not going to drive enough people away to ruin his profits, just like the NTR is not driving enough people away to hurt profits. Some people may be turned off and leave, yes, but not enough to make a serious negative impact on WWG's profits or hurt the production of the game.
WWG took a poll a long time ago, and nearly two-thirds of his patrons play the game with the NTR turned on. The NTR haters are not the majority. I think it will be the same with the trans content. Some people will love it, some people will just think it's funny, some people will be mostly neutral about it, some people will ignore it, some people will dislike but tolerate it, and a very small number of people will be so enraged by it's existence that they will stop supporting/playing. It will be a small number of people. They might be loud on their way out the door, but they will not be a significant number of people.
Look at the What If stories. Most of them are NTR, and the ideas come from suggestions from patrons which are then voted on by patrons. If there's a lean toward NTR, that's because that's what his supporters voted for. If we start getting lots of Drew related What If stories, that will mean that people are coming up with ideas for Drew and people are voting for those ideas. I'd bet anything that we'll be seeing some Drew content in the What If stories before long.